I have never been a big fan of repetitive movement or stress on the human body, much like an all night binger is on the body and causes it to break down.  Marathons tend to have a effect on the body that breaks it down, repetitive stress is tough on the body just read this story about the man collapsing and dying after running this marathon.. story below..
 

Marathoner Collapses, Dies
From Associated Press

March 02, 2008 4:23 PM EST

LITTLE ROCK, Ark. – A man who completed running the Little Rock Marathon on Sunday has collapsed and died.

Authorities haven’t released his name but said he was 27 years old and from outside Arkansas.

Emergency personal used mouth-to-mouth resuscitation. An ambulance arrived with a defibrillator, but the man could not be revived and was pronounced dead.